Successful Pregnancy After Therapeutic Apheresis in a Complex Case of PCOS, Hashimoto Thyroiditis, Recurrent Implantation Failure, and Potential Occupational Environmental Exposure

Philipp Och, Stefan R Bornstein, Charlotte Steenblock · 2026

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Description

Philipp Och is lead author of a 2026 single-case report of a successful pregnancy after therapeutic apheresis, a procedure that filters blood outside the body, in a woman with complex infertility. She was 33, had polycystic ovary syndrome and Hashimoto thyroiditis, an autoimmune thyroid condition, and had been infertile since 2020 despite several treatment cycles.

Fertility treatment with in vitro fertilisation and repeated embryo transfers began in 2023 without success. Apheresis was then added, aiming to lower markers of oxidative stress and possible workplace exposures, including mercury and anaesthetic gases from her work as a dentist. Pregnancy was documented in December 2024, and a healthy girl was born in September 2025. The authors stress a time link, not proof of cause.

Catalog record

CREATORPhilipp Och, Stefan R Bornstein, Charlotte Steenblock
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE20810
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13271147

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