Protective Effect of Salidroside Against Multiple Organs Ischemia-Reperfusion Injury: New Insights From Common and Specific Pharmacological Mechanisms

Xiansu Chi, Shuang Zheng, Chunyan Guo, Jiawei Wang, Ze Chang, Xiaoxuan Cao, Libin Jiang, Yunling Zhang, Wei Shen · 2026

Read Protective Effect of Salidroside Against Multiple Organs Ischemia-Reperfusion Injury: New Insights From Common and Specific Pharmacological Mechanisms by Xiansu Chi, Shuang Zheng, Chunyan Guo, Jiawei Wang, Ze Chang, Xiaoxuan Cao, Libin Jiang, Yunling Zhang, Wei Shen (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13271145.txt.

Description

Xiansu Chi is lead author of a 2026 narrative review on salidroside, a natural compound from traditional medicinal plants, as protection against ischemia-reperfusion injury. That injury is a paradox: restoring blood flow after a blockage can worsen tissue damage instead of saving the tissue, and each organ responds differently.

Searching two databases through February 2026, the authors summarise shared protective actions across organs, including cutting oxidative stress, calming inflammation, and limiting two forms of cell death. They also note organ-specific effects tied to each tissue's own damage pattern. Gaps, they say, include uneven evidence quality and no standard dosing, which block use in care and guide future formulation work.

Catalog record

CREATORXiansu Chi, Shuang Zheng, Chunyan Guo, Jiawei Wang, Ze Chang, Xiaoxuan Cao, Libin Jiang, Yunling Zhang, Wei Shen
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE70787
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13271145

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