A distributed analysis approach for pharmacovigilance data from electronic medical records in German university hospitals: the POLAR_MI ETL Pipeline

Miriam Kesselmeier, Torsten Thalheim, Florian Schmidt, Thomas Peschel, Julia Palm, Alexander Strübing, André Medek, Jens Przybilla, Anna Maria Wermund, Renke Maas, Steffen Härterich, Louisa Redeker, Martin Federbusch, Daniel Steinbach, Jan Gewehr, Marcus Wurlitzer, Andrea Riedel, Frank Meineke, Daniel Neumann, André Scherag, Markus Loeffler · 2026

Read A distributed analysis approach for pharmacovigilance data from electronic medical records in German university hospitals: the POLAR_MI ETL Pipeline by Miriam Kesselmeier, Torsten Thalheim, Florian Schmidt, Thomas Peschel, Julia Palm, Alexander Strübing, André Medek, Jens Przybilla, Anna Maria Wermund, Renke Maas, Steffen Härterich, Louisa Redeker, Martin Federbusch, Daniel Steinbach, Jan Gewehr, Marcus Wurlitzer, Andrea Riedel, Frank Meineke, Daniel Neumann, André Scherag, Markus Loeffler (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13270667.txt.

Description

Miriam Kesselmeier led a 2026 journal article on POLAR_MI, a German project that hunts for drug risks in patients taking many medicines at once. The work used routine hospital records held at German university hospitals, handled through each site's own data centre to protect privacy.

The team built a two-step method: each centre first gathered and summarised its own data locally, then a central team pooled the summaries. They describe the technical hurdles caused by differing local systems and how repeated rounds of fixes solved them. In the end the pipeline covered ten centres, nearly 800,000 hospital encounters, and about 500,000 patients.

Catalog record

CREATORMiriam Kesselmeier, Torsten Thalheim, Florian Schmidt, Thomas Peschel, Julia Palm, Alexander Strübing, André Medek, Jens Przybilla, Anna Maria Wermund, Renke Maas, Steffen Härterich, Louisa Redeker, Martin Federbusch, Daniel Steinbach, Jan Gewehr, Marcus Wurlitzer, Andrea Riedel, Frank Meineke, Daniel Neumann, André Scherag, Markus Loeffler
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE59784
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13270667

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