Clinicopathologic features and outcomes of patients with DNAJB9-positive fibrillary glomerulonephritis
Ozge Hurdogan, Safak Mirioglu, Egemen Cebeci, Ahmet Burak Dirim, Sidar Bagbudar, Cagla Safak Karaoglan, Ayse Serra Artan, Ozgur Akin Oto, Isin Kilicaslan, Savas Ozturk, Halil Yazici, Yasemin Ozluk · 2026
Read Clinicopathologic features and outcomes of patients with DNAJB9-positive fibrillary glomerulonephritis by Ozge Hurdogan, Safak Mirioglu, Egemen Cebeci, Ahmet Burak Dirim, Sidar Bagbudar, Cagla Safak Karaoglan, Ayse Serra Artan, Ozgur Akin Oto, Isin Kilicaslan, Savas Ozturk, Halil Yazici, Yasemin Ozluk (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13270315.txt.
Description
Ozge Hurdogan and colleagues study their patients with fibrillary glomerulonephritis. The very rare kidney disease is defined by non-branching fibril deposits and a positive DNAJB9 test. The study took in adult patients found over nearly two decades. Each showed DNAJB9 positivity on biopsy.
The team looked at fifty native kidney biopsies from forty-four patients. The most common injury patterns were mesangial and membranoproliferative. A minority showed atypical variants, such as congophilia and light-chain restriction. Follow-up ran for a median of about twenty-seven months. In that span, about half of the followed patients hit the composite outcome: doubled creatinine, kidney replacement therapy, advanced kidney disease, or death. Two in five had dialysis or a transplant. In regression models, hemoglobin predicted the main outcome.
Catalog record
| CREATOR | Ozge Hurdogan, Safak Mirioglu, Egemen Cebeci, Ahmet Burak Dirim, Sidar Bagbudar, Cagla Safak Karaoglan, Ayse Serra Artan, Ozgur Akin Oto, Isin Kilicaslan, Savas Ozturk, Halil Yazici, Yasemin Ozluk |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |