Sustained chlorhexidine susceptibility in clinical MRSA isolates despite recent exposure
Nadja Morello, Federica Andreoni, Willy I Staiger, Thomas C Scheier, David Weller, Ekaterina Vostokova, Silvio D Brugger · 2026
Read Sustained chlorhexidine susceptibility in clinical MRSA isolates despite recent exposure by Nadja Morello, Federica Andreoni, Willy I Staiger, Thomas C Scheier, David Weller, Ekaterina Vostokova, Silvio D Brugger (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13270236.txt.
Description
Nadja Morello and co-authors published a journal article in 2026 on whether MRSA bacteria, a drug-resistant hospital germ, are losing sensitivity to chlorhexidine, the antiseptic used to clear them from patients. Ninety-five isolates from 77 patients at a Zurich hospital in 2021 and 2022 were tested, with gene sequencing.
Most isolates were killed at low antiseptic levels, with the commonest growth-blocking level at 2 milligrams per liter in 76.6 percent. Ten isolates needing higher killing levels were repeatedly exposed to weak antiseptic doses, and none lost further sensitivity. Resistance genes were found but had no visible effect. Repeat isolates from seven patients stayed stable despite long carriage and exposure.
Catalog record
| CREATOR | Nadja Morello, Federica Andreoni, Willy I Staiger, Thomas C Scheier, David Weller, Ekaterina Vostokova, Silvio D Brugger |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33391 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |