Targeting the Zika virus envelope domains I and III as a recombinant vaccine protects mice from lethal challenge
Vincent Dussupt, Jaime L Jensen, Angélica Peña Rosado, Marissa Donofrio, Jill Pflugheber, Letzibeth Mendez-Rivera, Rajeshwer S Sankhala, Wei-Hung Chen, Bonnie M Slike, Annika Schmid, Ursula Tran, Lily Metzger, Caroline E Peterson, Amelia K Pinto, Sandhya Vasan, Natalie D Collins, Aaron Farmer, Nelso · 2026
Read Targeting the Zika virus envelope domains I and III as a recombinant vaccine protects mice from lethal challenge by Vincent Dussupt, Jaime L Jensen, Angélica Peña Rosado, Marissa Donofrio, Jill Pflugheber, Letzibeth Mendez-Rivera, Rajeshwer S Sankhala, Wei-Hung Chen, Bonnie M Slike, Annika Schmid, Ursula Tran, Lily Metzger, Caroline E Peterson, Amelia K Pinto, Sandhya Vasan, Natalie D Collins, Aaron Farmer, Nelso (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13270120.txt.
Description
Zika virus (ZIKV) vaccine candidates developed through Phase I clinical trials are based on the full-length envelope glycoprotein (E), which presents both desirable and undesirable antigenic determinants. Among the latter, the conserved fusion loop epitope (FLE) within domain II is a major target for flavivirus cross-reactive and poorly neutralizing responses.
Catalog record
| CREATOR | Vincent Dussupt, Jaime L Jensen, Angélica Peña Rosado, Marissa Donofrio, Jill Pflugheber, Letzibeth Mendez-Rivera, Rajeshwer S Sankhala, Wei-Hung Chen, Bonnie M Slike, Annika Schmid, Ursula Tran, Lily Metzger, Caroline E Peterson, Amelia K Pinto, Sandhya Vasan, Natalie D Collins, Aaron Farmer, Nelso |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |