Compartment-based biomarker integration for clinical monitoring in eosinophilic esophagitis
Adam Wawrzeńczyk, Katarzyna Napiórkowska-Baran, Marta Tykwińska, Maciej Szota, Zbigniew Bartuzi, Józef Sławatycki, Alina Kanikowska, Krzysztof Pałgan · 2026
Read Compartment-based biomarker integration for clinical monitoring in eosinophilic esophagitis by Adam Wawrzeńczyk, Katarzyna Napiórkowska-Baran, Marta Tykwińska, Maciej Szota, Zbigniew Bartuzi, Józef Sławatycki, Alina Kanikowska, Krzysztof Pałgan (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13269977.txt.
Description
Adam Wawrzeńczyk and co-authors published a review in 2026 on biomarkers for monitoring eosinophilic esophagitis, a chronic immune disease of the food pipe. Symptoms match tissue activity poorly, so patients need repeated camera scopes. The review sorts candidate markers by body compartment: tissue, fluids near the tissue, and blood.
Signals tied to type 2 inflammation define the disease but measure weakly in blood. Tissue gene signatures and markers sampled close to the food pipe tracked inflammation and treatment response far better. Structural markers showed that tissue healing does not always mean the lining is restored. The authors propose combining molecular and low-burden tools to cut scope use, after prospective testing.
Catalog record
| CREATOR | Adam Wawrzeńczyk, Katarzyna Napiórkowska-Baran, Marta Tykwińska, Maciej Szota, Zbigniew Bartuzi, Józef Sławatycki, Alina Kanikowska, Krzysztof Pałgan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47815 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |