Synthesis, Characterization, and Anticancer Activity of Vanadium (III) Complexes With Pyridyl–Triazole Ligands

Yair Alvarez-Ricardo, Deissy N Jaramillo, Adrian Leonardo Orjuela, Elizabeth Jiménez-Díaz, Jorge Alí-Torres, Mario A Macías, Antonino Arenaza-Corona, David Morales-Morales, John J Hurtado, Anastasios Keramidas · 2026

Read Synthesis, Characterization, and Anticancer Activity of Vanadium (III) Complexes With Pyridyl–Triazole Ligands by Yair Alvarez-Ricardo, Deissy N Jaramillo, Adrian Leonardo Orjuela, Elizabeth Jiménez-Díaz, Jorge Alí-Torres, Mario A Macías, Antonino Arenaza-Corona, David Morales-Morales, John J Hurtado, Anastasios Keramidas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13269649.txt.

Description

Yair Alvarez-Ricardo and co-authors published a journal article in 2026 on three new vanadium compounds built with ring-shaped partner molecules, tested against cancer cells. Their structures were checked with standard lab methods, and one was mapped exactly by X-ray crystallography, a method that reveals atomic layout.

Across six human cancer cell lines, the compounds beat the common drug cisplatin in five, needing lower doses to halve cell growth. One compound was strongest against a lung cancer line, and another against a colon cancer line. Unlike cisplatin, they barely harmed healthy fiber cells. One compound pushed lung cancer cells into late-stage programmed death without tissue-rotting death. Computer studies also showed the compounds stick to DNA.

Catalog record

CREATORYair Alvarez-Ricardo, Deissy N Jaramillo, Adrian Leonardo Orjuela, Elizabeth Jiménez-Díaz, Jorge Alí-Torres, Mario A Macías, Antonino Arenaza-Corona, David Morales-Morales, John J Hurtado, Anastasios Keramidas
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE71613
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13269649

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