Pre-discharge neutrophil:lymphocyte ratio and lymphopenia are associated with post-hospital long-term outcomes among survivors of critical illness
Lucas L. Marinho, John C. Marshall, Danielle Jeong, Dennis T. Ko, Patrick R. Lawler · 2026
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Description
Lucas L Marinho and co-authors wrote a letter to the editor in 2026 on blood markers measured just before hospital discharge in survivors of critical illness. Two simple counts were tested: the ratio of two white cell types, and a low count of lymphocytes, a white cell type that fights infection. The outcome was death within one year.
Records came from a Boston intensive care database covering 2008 to 2022. Of 20,906 eligible survivors, 1,052 had both measures taken within 72 hours before discharge. Their median ratio was 4.2, and 26 percent had the low lymphocyte count. Higher ratios and low counts tracked with greater illness severity and more other diseases. The authors present the markers as cheap tools for spotting higher-risk survivors at discharge.
Catalog record
| CREATOR | Lucas L. Marinho, John C. Marshall, Danielle Jeong, Dennis T. Ko, Patrick R. Lawler |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12434 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |