Clinical benefit of paclitaxel/carboplatin plus bevacizumab with zoledronic acid in pulmonary epithelioid hemangioendothelioma complicated by hypertrophic pulmonary osteoarthropathy and cardiac tamponade: a case report
Saki Tsuchimochi, Hiromichi Nakajima, Yukako Hattori, Shioto Oda, Hiroki Imada, Tetsuro Taki, Anna Matsuoka, Shogo Watanabe, Akira Hirota, Mai Shimura, Misao Fukuda, Chikako Funasaka, Kenichi Harano, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Genichiro Ishii, Toru Mukohara · 2026
Read Clinical benefit of paclitaxel/carboplatin plus bevacizumab with zoledronic acid in pulmonary epithelioid hemangioendothelioma complicated by hypertrophic pulmonary osteoarthropathy and cardiac tamponade: a case report by Saki Tsuchimochi, Hiromichi Nakajima, Yukako Hattori, Shioto Oda, Hiroki Imada, Tetsuro Taki, Anna Matsuoka, Shogo Watanabe, Akira Hirota, Mai Shimura, Misao Fukuda, Chikako Funasaka, Kenichi Harano, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Genichiro Ishii, Toru Mukohara (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13269039.txt.
Description
Saki Tsuchimochi and a large team report in 2026 a case where chemotherapy plus targeted drugs eased a rare lung vessel tumor and its painful bone complication. The patient, a 33-year-old woman, had chronic cough, joint pain, and clubbed fingers. Scans showed a lung mass invading the chest center, swollen nodes, and fluid squeezing her heart, which needed emergency drainage.
Biopsies confirmed epithelioid hemangioendothelioma, a rare vessel-lining cancer with no standard drug regimen. She received two chemotherapy drugs plus a vessel-blocking antibody, while a bone drug treated the overgrowth syndrome around her joints. Fluid around heart and lungs shrank markedly, joint pain eased, and daily function improved. The benefit faded with time, yet the case suggests the combination can buy meaningful relief.
Catalog record
| CREATOR | Saki Tsuchimochi, Hiromichi Nakajima, Yukako Hattori, Shioto Oda, Hiroki Imada, Tetsuro Taki, Anna Matsuoka, Shogo Watanabe, Akira Hirota, Mai Shimura, Misao Fukuda, Chikako Funasaka, Kenichi Harano, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Genichiro Ishii, Toru Mukohara |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |