Cyclic Alternating Pattern and Sleep Microstructure in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Jiajun Jiang, Yi Huang, Min Wang, Zixuan Zeng, Jing Li · 2026
Read Cyclic Alternating Pattern and Sleep Microstructure in Parkinson’s Disease: A Systematic Review and Meta-Analysis by Jiajun Jiang, Yi Huang, Min Wang, Zixuan Zeng, Jing Li (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13269027.txt.
Description
Jiajun Jiang and co-authors published a review and combined analysis in 2026 on sleep in Parkinson's disease. They focused on the cyclic alternating pattern, a repeating rhythm seen in brain activity during sleep. The question was whether this rhythm differs between patients and healthy people.
Searching five databases for studies from 2020 to 2025, the team found only four studies that fit their rules. Patients showed lower pattern rates, shorter pattern sequences, and lower pattern index scores than healthy controls. Broader sleep measures showed no clear pooled difference. The authors rate the proof as very low in strength and say the sleep measures are not yet proven markers of the disease.
Catalog record
| CREATOR | Jiajun Jiang, Yi Huang, Min Wang, Zixuan Zeng, Jing Li |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44715 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |