Fever of Unknown Origin as an Isolated Manifestation of Ulcerative Colitis Despite Clinical and Radiographic Remission: A Case Report

Muhammad Memon · 2026

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Description

Muhammad Memon presents a 2026 case report on fever as the only sign of ulcerative colitis. Ulcerative colitis inflames the colon and usually causes diarrhea and bleeding; fever normally comes with active gut disease. His patient was a 68-year-old woman with well-controlled HIV and newly diagnosed colitis, on gut-targeted biologic therapy. She developed daily persistent fevers.

Scans showed her colitis had resolved, and she had no gut symptoms at all. An extensive hunt for infection, cancer, clots, and autoimmune disease found nothing. Her blood counts dropped and inflammation markers soared; she even developed an irregular heartbeat during the illness. With every other cause excluded, the team blamed an atypical body-wide flare of her colitis. Memon urges clinicians to consider this rare pattern once infection is rigorously ruled out.

Catalog record

CREATORMuhammad Memon
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE19048
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13268708

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