The role of ultrasound of the quadriceps femoris in people with cystic fibrosis: a systematic review and meta-analysis
Jorge Eduardo Cortz Sernaglia, Aline Priscila de Souza, Aline Cristina Gonçalves, Daniela de Souza Paiva Borgli, Carla Cristina Souza Gomez, José Dirceu Ribeiro · 2026
Read The role of ultrasound of the quadriceps femoris in people with cystic fibrosis: a systematic review and meta-analysis by Jorge Eduardo Cortz Sernaglia, Aline Priscila de Souza, Aline Cristina Gonçalves, Daniela de Souza Paiva Borgli, Carla Cristina Souza Gomez, José Dirceu Ribeiro (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13268511.txt.
Description
Jorge Eduardo Cortz Sernaglia and colleagues present a 2026 systematic review and meta-analysis on ultrasound of the thigh muscle in cystic fibrosis. Muscle loss is a hallmark of the disease and predicts worse outcomes, but measuring it usually needs costly scans. Ultrasound at the bedside could track the quadriceps, the big front thigh muscle. The team searched six databases for studies measuring quadriceps size by ultrasound in people with CF.
Only five studies qualified. People with CF had thinner quadriceps and smaller cross-sections than controls, especially when malnourished. Ultrasound measures tracked moderately with lung function, lean body mass, and strength. Pooling showed a clear thickness deficit versus controls, though studies varied a lot. Bias risk was moderate, driven by small samples. The authors call for bigger, better studies before ultrasound guides care.
Catalog record
| CREATOR | Jorge Eduardo Cortz Sernaglia, Aline Priscila de Souza, Aline Cristina Gonçalves, Daniela de Souza Paiva Borgli, Carla Cristina Souza Gomez, José Dirceu Ribeiro |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49189 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |