Serum human epididymis protein 4, endocan, sialyl-Tn, and neopterin in endometrial cancer: a prospective case–control study

Atahan Toyran, Yagmur Minareci, Hamdullah Sözen, Canan Kucukgergin, Abdurrahman Fatih Aydın, İlknur Bingul, Mehmet Guven Gunver, Serra Zeynep Akkoyunlu, Samet Topuz, Mehmet Yavuz Salihoglu · 2026

Read Serum human epididymis protein 4, endocan, sialyl-Tn, and neopterin in endometrial cancer: a prospective case–control study by Atahan Toyran, Yagmur Minareci, Hamdullah Sözen, Canan Kucukgergin, Abdurrahman Fatih Aydın, İlknur Bingul, Mehmet Guven Gunver, Serra Zeynep Akkoyunlu, Samet Topuz, Mehmet Yavuz Salihoglu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13268230.txt.

Description

Atahan Toyran and colleagues present a 2026 study testing four blood markers for womb cancer. Endometrial cancer is common, but no reliable blood test exists for early detection. The team measured the markers (endocan, HE4, sialyl-Tn, and neopterin) before treatment in 133 women with the cancer and 65 healthy women.

Endocan and HE4 levels were clearly higher in cancer patients than in controls, and each separated the groups moderately well. Neopterin and sialyl-Tn showed no difference and no diagnostic value. Endocan and HE4 were also higher when cancer had entered nearby tissue spaces, though that link weakened after statistical correction. The authors call the findings exploratory and say larger, clinically realistic studies must confirm them before any test reaches practice.

Catalog record

CREATORAtahan Toyran, Yagmur Minareci, Hamdullah Sözen, Canan Kucukgergin, Abdurrahman Fatih Aydın, İlknur Bingul, Mehmet Guven Gunver, Serra Zeynep Akkoyunlu, Samet Topuz, Mehmet Yavuz Salihoglu
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE21797
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13268230

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