Acute promyelocytic leukaemia presenting with gingival hypertrophy: an atypical oral presentation
Emmanuel Kissiedu Antiri, Ivy Adwowa Efiefi Ekem · 2026
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Description
Emmanuel Kissiedu Antiri and Ivy Adwowa Efiefi Ekem present a 2026 case report on a leukemia that first showed in the gums. Acute promyelocytic leukemia is a fast blood cancer with a known gene fusion and a high early death risk if treatment lags. Their patient was a 26-year-old man whose gums grew steadily larger over three weeks. Swollen gums are a rare sign for this subtype.
He was treated for gum inflammation for two weeks before blood work was done. Marrow tests and gene probes then confirmed the leukemia, in its microgranular form. Blood counts were low, but there was no severe bleeding disorder, which made the picture atypical. The standard targeted drug was unavailable locally, so standard chemotherapy was given. He died one week into treatment. The authors stress fast referral when gums swell oddly.
Catalog record
| CREATOR | Emmanuel Kissiedu Antiri, Ivy Adwowa Efiefi Ekem |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 14682 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |