Effects of Menopausal Hormone Therapy on Uterine Fibroids in Women During Menopausal Transition

Mengqi Huang, Jie Chen, Lin Gu, Yuxuan Yang, Pengfei Qin · 2026

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Description

Mengqi Huang and colleagues wrote a 2026 study of hormone therapy and womb growths during the menopause transition. Uterine fibroids are common non-cancer growths that react to hormones. Whether menopausal hormone therapy makes them grow was unclear. The team followed 83 women at a Nanjing hospital who took a standard two-hormone sequence from 2016 onward, with repeat ultrasound scans.

Fibroid area shifted slightly during the first four years, in ways the team judged too small to matter in practice. By year five no difference from the start could be detected. Side effects were mostly brief and faded on their own. Unexpected bleeding affected about 18 percent, breast discomfort about 11 percent, and stomach symptoms about 2 percent. The authors call the therapy a safe option with regular checks.

Catalog record

CREATORMengqi Huang, Jie Chen, Lin Gu, Yuxuan Yang, Pengfei Qin
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE30220
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13267823

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