A Phase 2 Study of the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Patients With Pulmonary Hypertension Associated With Interstitial Lung Disease
Colin Church, Maria Molina‐Molina, Miguel Arias‐Guillén, Patrick Muchmore, Ben R Lavon, Jan De Backer, Natalya Makulova, Bipin Mistry, Jia Guo, Jasmanda Wu, Junaideen Fahumy, Ariel Teper, Peng‐Liang Zhao, Kevin C Mange, Gerald O'Brien · 2026
Read A Phase 2 Study of the Safety and Tolerability of Treprostinil Palmitil Inhalation Powder in Patients With Pulmonary Hypertension Associated With Interstitial Lung Disease by Colin Church, Maria Molina‐Molina, Miguel Arias‐Guillén, Patrick Muchmore, Ben R Lavon, Jan De Backer, Natalya Makulova, Bipin Mistry, Jia Guo, Jasmanda Wu, Junaideen Fahumy, Ariel Teper, Peng‐Liang Zhao, Kevin C Mange, Gerald O'Brien (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13267426.txt.
Description
Colin Church and colleagues report a 2026 phase 2 trial of an inhaled powder for high blood pressure in scarred lungs. The drug is a long-acting form of treprostinil, which widens lung blood vessels. Adults with pulmonary hypertension tied to interstitial lung disease were given the powder or a placebo once a day for 16 weeks.
The trial enrolled 29 patients on the drug and 10 on placebo. Most reached the top daily dose, and side effects matched those known for inhaled forms, such as cough and breathlessness. Serious side effects were less common in the drug group than in the placebo group. Fewer treated patients worsened during the trial. Walking distance and a heart strain marker also trended better, leading the authors to back further study.
Catalog record
| CREATOR | Colin Church, Maria Molina‐Molina, Miguel Arias‐Guillén, Patrick Muchmore, Ben R Lavon, Jan De Backer, Natalya Makulova, Bipin Mistry, Jia Guo, Jasmanda Wu, Junaideen Fahumy, Ariel Teper, Peng‐Liang Zhao, Kevin C Mange, Gerald O'Brien |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55280 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |