Rethinking flow: the paradox of renoprotection without increased renal blood flow in cardiopulmonary bypass

Shiksha Mohan, Ronald A. Shaju, Sharan Misra, Titiksha Sharma, Veeraj K. Sirivolu, Abhinav Rajkumar, Anthony Rodas-Camacho, Aizah Zaidi, Dhruv Dhingra, Ilma Khan, Rishav Bhattacharya, Vishal Pancholy, Shivam Banerjee, Shreyo Ghosh, Shiyi Li, Kenneth K. Liao, Carl P. Walther, Nandan K. Mondal · 2026

Read Rethinking flow: the paradox of renoprotection without increased renal blood flow in cardiopulmonary bypass by Shiksha Mohan, Ronald A. Shaju, Sharan Misra, Titiksha Sharma, Veeraj K. Sirivolu, Abhinav Rajkumar, Anthony Rodas-Camacho, Aizah Zaidi, Dhruv Dhingra, Ilma Khan, Rishav Bhattacharya, Vishal Pancholy, Shivam Banerjee, Shreyo Ghosh, Shiyi Li, Kenneth K. Liao, Carl P. Walther, Nandan K. Mondal (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13266870.txt.

Description

Shiksha Mohan and a large group of co-authors examine in 2026 a puzzling trial result about kidney protection during heart-lung bypass. Kidney injury strikes a sizable share of patients after heart surgery, and low oxygen delivery is a suspected cause. The trial they discuss raised pump flow by about a fifth in 36 patients and measured kidney function with precise catheter methods.

Higher flow improved filtration and reduced signs of tubule injury, yet total blood flow through the kidney did not rise. Oxygen supply and demand for the kidney as a whole also stayed similar. That split outcome pushes attention toward how blood is shared inside the kidney, rather than toward simple total flow numbers.

Catalog record

CREATORShiksha Mohan, Ronald A. Shaju, Sharan Misra, Titiksha Sharma, Veeraj K. Sirivolu, Abhinav Rajkumar, Anthony Rodas-Camacho, Aizah Zaidi, Dhruv Dhingra, Ilma Khan, Rishav Bhattacharya, Vishal Pancholy, Shivam Banerjee, Shreyo Ghosh, Shiyi Li, Kenneth K. Liao, Carl P. Walther, Nandan K. Mondal
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE14 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13266870

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