Effectiveness and safety of cryoablation therapy for early-stage lung cancer patients: a systematic review and meta-analysis
Kun Zhang, Han Wu, Wentong Zhang, Tianlan Wang, Bo Huang, Lei Cao · 2026
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Description
Kun Zhang and colleagues pool in 2026 the results of freezing therapy for early-stage lung cancer, for patients who often cannot face major surgery. Their meta-analysis gathered seven small studies covering 353 patients, most with stage IA disease. They tracked survival, cancer control, local return of tumor, spread, and procedure harms.
Survival stayed high through three years, then fell by year five, a pattern the authors report without a direct surgery comparison. Local recurrence and spread were uncommon in the pooled data. Collapsed lung was the most frequent harm, affecting about a quarter of patients, while no deaths occurred within thirty days. Stage IA patients fared best, supporting freezing as an option for carefully chosen cases.
Catalog record
| CREATOR | Kun Zhang, Han Wu, Wentong Zhang, Tianlan Wang, Bo Huang, Lei Cao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |