Narrative review: clinical application and challenges of circulating tumor DNA in treatment response evaluation and prognostic prediction for esophageal cancer
Rentong Gu, Tao Liu, Hai Jin, Xiaowei Wang · 2026
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Description
Rentong Gu and colleagues review in 2026 how tumor DNA found in blood can track treatment response and outlook in esophageal cancer. Fragments shed by tumors allow repeated, non-invasive checks of cancer burden without new biopsies. The authors searched the literature from 2015 to early 2026, favoring clinical studies and prior reviews.
When this DNA cleared during pre-surgery treatment, patients more often had no tumor left at operation. Finding it after surgery consistently signaled higher relapse risk and shorter survival, and certain mutations added further detail. Barriers include uneven test standards, false signals from blood cell changes, and cost. Combining DNA data with imaging and other measures may sharpen its use.
Catalog record
| CREATOR | Rentong Gu, Tao Liu, Hai Jin, Xiaowei Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |