Research progress on immune microenvironment and biomarkers of small cell lung cancer
Na Di, Heping Sun, Qi Wang, Rui Zhong, Lin Tian, Peiyan Zhao, Hui Li, Haifeng Liu · 2026
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Description
Na Di and co-authors review in 2026 the immune surroundings and marker proteins of small cell lung cancer. This fast-growing cancer spreads early, returns often, and still leaves few patients alive at five years. Immune checkpoint drugs help some patients, yet durable responses remain uncommon because the tumor environment tends to shut immune cells out.
Drawing on gene sequencing, single-cell studies, and spatial mapping, the review compares limited-stage, extensive-stage, relapsed, and never-smoker forms of the disease. It sorts the immune features and biomarkers reported for each form. That organized picture may help researchers choose better drug combinations and find new weak points to target in future trials.
Catalog record
| CREATOR | Na Di, Heping Sun, Qi Wang, Rui Zhong, Lin Tian, Peiyan Zhao, Hui Li, Haifeng Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |