Integrating measures of remnant cholesterol and inflammation: risky business?
Josiah Bennett, Jose R. Medina-Inojosa, Laurence S. Sperling · 2026
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Description
Josiah Bennett and two co-authors weighed a two-part risk measure for heart disease in a piece from two thousand twenty-six. Remnant cholesterol is the part left in fat-rich particles after the standard low-density lipoprotein and high-density lipoprotein fractions are counted. Gene studies since two thousand thirteen have shown it drives artery disease on its own, in part through low-grade inflammation in vessel walls. Most American adults now meet criteria for the linked heart, kidney, and metabolic syndrome.
Even when low-density lipoprotein is well controlled, risk still runs along two axes, the authors note. One axis holds leftover particles, and the other holds inflammation. Putting the two measures into one view is the risky business named in the title. The piece reviews the evidence and asks whether combined scores sharpen prevention or add noise.
Catalog record
| CREATOR | Josiah Bennett, Jose R. Medina-Inojosa, Laurence S. Sperling |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 8 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |