Effects of multidomain interventions on health outcomes in older adults: A systematic review and meta-analysis
Eleonora Pagan, Chukwuma Okoye, Luca Cuffaro, Alice Margherita Ornago, Alberto Finazzi, Federico Emanuele Pozzi, Maria Cristina Ferrara, Carlo Custodero, Vittorio Dibello, Alessandra Palladini, Gessica Sala, Vincenzo Solfrizzi, Antonella Zambon, Carlo Ferrarese, Giuseppe Bellelli · 2026
Read Effects of multidomain interventions on health outcomes in older adults: A systematic review and meta-analysis by Eleonora Pagan, Chukwuma Okoye, Luca Cuffaro, Alice Margherita Ornago, Alberto Finazzi, Federico Emanuele Pozzi, Maria Cristina Ferrara, Carlo Custodero, Vittorio Dibello, Alessandra Palladini, Gessica Sala, Vincenzo Solfrizzi, Antonella Zambon, Carlo Ferrarese, Giuseppe Bellelli (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13265428.txt.
Description
Eleonora Pagan, Chukwuma Okoye, Luca Cuffaro, and a wider team wrote this systematic review, published in 2026. It pools trials of multidomain programs for older adults, packages that train body, mind, and diet together, to see what they do for health.
The review covered thirty-eight studies in people aged sixty and up without major dementia, lasting two months to three years. Every program included exercise; most added cognitive and nutritional parts, and many added more. Physical performance improved clearly, and frailty scores eased. The analysis also tracked thinking and mood outcomes with standard statistical pooling. The authors say combined programs beat single-fix thinking for aging well. The open question is which ingredients and doses matter most, since programs varied widely across the trials pooled.
Catalog record
| CREATOR | Eleonora Pagan, Chukwuma Okoye, Luca Cuffaro, Alice Margherita Ornago, Alberto Finazzi, Federico Emanuele Pozzi, Maria Cristina Ferrara, Carlo Custodero, Vittorio Dibello, Alessandra Palladini, Gessica Sala, Vincenzo Solfrizzi, Antonella Zambon, Carlo Ferrarese, Giuseppe Bellelli |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |