Research Progress of SGLT2 Inhibitors in the Treatment of Acute Heart Failure: A Narrative Review
Xiaoying Wang, Yuanyuan Ning, Xiaojuan Wang, Guangli Li, Xiaowu Wang, Dong Wu · 2026
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Description
Xiaoying Wang and colleagues review SGLT2 inhibitor drugs for acute heart failure, in a 2026 narrative review. These diabetes drugs have shown clear benefits in chronic heart failure. Their use during sudden worsening is attracting attention. Evidence available up to March 2026 was summarised.
Early starting during acute episodes appears generally safe. The drugs improve fluid removal, ease congestion, and reduce later heart failure events. Findings on short-term readmission remain inconsistent. Best timing and safety in particular patient groups stay unresolved. Key trials and real-world studies are discussed to guide practice and future research.
Catalog record
| CREATOR | Xiaoying Wang, Yuanyuan Ning, Xiaojuan Wang, Guangli Li, Xiaowu Wang, Dong Wu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |