T4bN0 colon cancer shows worse survival than T1–2N1 disease: a multicenter real-world study in China
Xin Li, Lei Liang, Zhen-Ya Yang, Jun-Nan Li, Ning Xu, Jun Yang · 2026
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Description
Xin Li and colleagues compare deeply invasive colon cancer without node spread against early node-positive disease, in a 2026 Chinese multicentre study. Current staging ranks node-positive disease as more advanced. Growing evidence suggests the deepest tumours may fare worse. Records from three centres covered surgery from 2014 to 2024.
The cohort held 391 patients across three stage groups. The deepest tumours, called T4bN0, showed worse features and worse survival than early node-positive cases. Another deep group did not differ clearly. A tumour marker subgroup also showed an unfavourable pattern. The authors question whether staging should weigh depth more heavily.
Catalog record
| CREATOR | Xin Li, Lei Liang, Zhen-Ya Yang, Jun-Nan Li, Ning Xu, Jun Yang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |