Identification and validation of tumor microenvironment remodeling markers associated with prognosis in differentiated thyroid cancer
Xiaokang Liu, Qiang Ma, Dai Su, Yu Li, Xiangting Zeng, Liang Guo · 2026
Read Identification and validation of tumor microenvironment remodeling markers associated with prognosis in differentiated thyroid cancer by Xiaokang Liu, Qiang Ma, Dai Su, Yu Li, Xiangting Zeng, Liang Guo (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13265194.txt.
Description
Xiaokang Liu and colleagues search for gene markers tied to tumour surroundings in differentiated thyroid cancer, in a 2026 study. Remodelling of the tissue around a tumour helps it grow and spread. Which remodelling genes predict outlook was unclear. The team combined clustering with many machine learning models.
Patients grouped into three molecular clusters. Testing of 101 models highlighted five key genes. The signature forecast one-, two-, and three-year survival with very high accuracy. Laboratory checks on patient samples confirmed the gene patterns. One gene was raised in tumours while the other four were lowered. The signature offers a new prognostic lead.
Catalog record
| CREATOR | Xiaokang Liu, Qiang Ma, Dai Su, Yu Li, Xiangting Zeng, Liang Guo |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |