Pan-tissue transcriptomic profiling of dairy cattle

Jinfeng He, Ruike Jia, Aixia Du, Weijie Zheng, Bo Han, Qi Zhang, Zijiao Guo, Yanan Liu, Yali Hou, Dongxiao Sun · 2026

Read Pan-tissue transcriptomic profiling of dairy cattle by Jinfeng He, Ruike Jia, Aixia Du, Weijie Zheng, Bo Han, Qi Zhang, Zijiao Guo, Yanan Liu, Yali Hou, Dongxiao Sun (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13264825.txt.

Description

Jinfeng He and colleagues published a 2026 data study profiling gene activity across the whole body of dairy cattle. Milk output depends on programs running in many tissues, yet past work looked mainly at the udder and liver. The team built a body-wide map that also covers gene splicing and other fine steps of gene use.

They sequenced RNA from 99 tissues of two Holstein cows and merged the data with 400 public samples from 182 cows, reaching 166 tissues in all. Busy tissues like brain, udder, and reproductive organs held the most tissue-only genes. Two splicing patterns dominated across tissues. Comparing 11,547 shared genes across cattle, humans, and pigs, matching organs grouped together across species. The authors offer the map as a resource for milk trait research.

Catalog record

CREATORJinfeng He, Ruike Jia, Aixia Du, Weijie Zheng, Bo Han, Qi Zhang, Zijiao Guo, Yanan Liu, Yali Hou, Dongxiao Sun
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE70140
LICENSEhttps://creativecommons.org/publicdomain/zero/1.0
RIGHTSCC0
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13264825

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