More than malaria: Exploring Babesia, Leishmania and Trypanosoma in sickle cell disease
Chanakya R Bhosale, Zachary L Morcos, Amanda Escudero, Raghavee Neupane, Zaneh Kahook, Genessiss Miranda, Emily Deehan, Randal K Gregg, Anna K Potter · 2026
Read More than malaria: Exploring Babesia, Leishmania and Trypanosoma in sickle cell disease by Chanakya R Bhosale, Zachary L Morcos, Amanda Escudero, Raghavee Neupane, Zaneh Kahook, Genessiss Miranda, Emily Deehan, Randal K Gregg, Anna K Potter (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13264320.txt.
Description
Chanakya R Bhosale and colleagues review three vector-borne parasites in people with sickle cell disease in a 2026 narrative review. Malaria interactions with sickle cell disease are well known, yet Babesia, Leishmania and Trypanosoma parasites are spreading through wider vector ranges, travel and blood transfusion. Each parasite hides in a different host compartment: red cells, immune scavenger cells, muscle or open bloodstream, which shapes illness and drug response in distinct ways for patients.
Sickle cell disease deforms red cells, causes chronic breakdown and vessel blockage, and damages organs over time. Those changes may alter susceptibility and severity for each parasite differently. The review gathers scattered evidence on mechanisms, symptoms and management to guide clinicians meeting these combined conditions.
Catalog record
| CREATOR | Chanakya R Bhosale, Zachary L Morcos, Amanda Escudero, Raghavee Neupane, Zaneh Kahook, Genessiss Miranda, Emily Deehan, Randal K Gregg, Anna K Potter |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 57 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |