Distance-adaptive geometric margins for residual rotational uncertainty in single-isocenter multitarget stereotactic radiosurgery
Jiaxin Deng, Zun Piao, Xinyu Song, Danyang Li, Jiang Hu, Shouliang Ding, Yanfei Liu, Li Chen, Guanqun Zhou, Ying Sun, Xiaoyan Huang, Guangyu Wang · 2026
Read Distance-adaptive geometric margins for residual rotational uncertainty in single-isocenter multitarget stereotactic radiosurgery by Jiaxin Deng, Zun Piao, Xinyu Song, Danyang Li, Jiang Hu, Shouliang Ding, Yanfei Liu, Li Chen, Guanqun Zhou, Ying Sun, Xiaoyan Huang, Guangyu Wang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13264242.txt.
Description
Jiaxin Deng and co-authors compute safety margins for brain radiosurgery that treats many tumors from one pivot point. Their 2026 study notes a flaw in the single-pivot method: tiny leftover turns shift far targets more than near ones, which risks a miss. The team derives a formula for that shift and checks it against a million fake targets.
The formula matched exact math to within a fifth of a millimeter. With a fixed one millimeter margin, pass rates fell off a cliff near one hundred millimeters from the pivot. Needed margins topped three millimeters at one hundred fifty. Margins that grow with distance, plus tighter turn control, can shield far targets without dosing extra healthy tissue.
Catalog record
| CREATOR | Jiaxin Deng, Zun Piao, Xinyu Song, Danyang Li, Jiang Hu, Shouliang Ding, Yanfei Liu, Li Chen, Guanqun Zhou, Ying Sun, Xiaoyan Huang, Guangyu Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |