Utilizing intraoperative frozen section examination (IFSE) for diagnosis and treatment in a high-clinical-suspicion prostate cancer (PCa) cohort based on 18F-PSMA PET/CT and MRI: a pilot study
Liang-Yong Zhu, Min Fang, Yang Luan, Tian-Bao Huang, Sheng-Ming Lu, Qin Xiao, Ji Chen, Xiao Tan, Xue-Fei Ding · 2026
Read Utilizing intraoperative frozen section examination (IFSE) for diagnosis and treatment in a high-clinical-suspicion prostate cancer (PCa) cohort based on 18F-PSMA PET/CT and MRI: a pilot study by Liang-Yong Zhu, Min Fang, Yang Luan, Tian-Bao Huang, Sheng-Ming Lu, Qin Xiao, Ji Chen, Xiao Tan, Xue-Fei Ding (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13263890.txt.
Description
Liang-Yong Zhu and colleagues piloted in 2026 a one-stop path for men whose scans shout prostate cancer. A rapid frozen reading of biopsy tissue confirms cancer, and removal follows at once in the same operation. Candidates needed both a very hot tracer scan and a top-tier MRI suspicion score. Fifty-six men enrolled between 2021 and 2024.
Frozen section confirmed cancer in every enrolled patient, a perfect hit rate for the strict imaging gate. All fifty-six completed biopsy and prostate removal in a single session. Final pathology found positive margins in nineteen men and seminal vesicle invasion in four. Continence returned fully within three months across the group. Twenty-seven men received further therapy afterward, and no biochemical recurrence appeared during follow-up. The authors call the pathway feasible and a useful complement, while admitting standards and safety need fuller definition.
Catalog record
| CREATOR | Liang-Yong Zhu, Min Fang, Yang Luan, Tian-Bao Huang, Sheng-Ming Lu, Qin Xiao, Ji Chen, Xiao Tan, Xue-Fei Ding |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |