Allogeneic Stem Cell Transplantation in Patients With Mixed Chimerism Following Double Cord Blood Transplantation: A Case Report
Youngrok Park, Seonghan Lee, Jinhang Kim, Jeong-A Kim · 2026
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Description
Youngrok Park and colleagues describe a clever second transplant strategy after cord blood transplantation in a 2026 case report. Their patient, aged 38, had a B-cell lymphoma that returned after a first stem cell transplant. With no matched donor for his own tissue type, he received cord blood from two donors, and unusually, cells from both persisted side by side.
When the cancer relapsed again and was beaten back, the team used the dominant cord donor's tissue type as the target for finding a new donor. A matched donor was found on that basis. The second transplant took hold fully, caused no graft-versus-host disease, and the patient stayed relapse-free for over four years. The authors offer the approach for similar rare cases.
Catalog record
| CREATOR | Youngrok Park, Seonghan Lee, Jinhang Kim, Jeong-A Kim |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 12852 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |