Hemostasis at the edge between physiology and cancer
Angela Galardi, Elisa Dell’Orto, Francesca Bianchi, Giulia Cosentino, Valentina Fogazzi, Serenella M. Pupa, Marilena V. Iorio · 2026
Read Hemostasis at the edge between physiology and cancer by Angela Galardi, Elisa Dell’Orto, Francesca Bianchi, Giulia Cosentino, Valentina Fogazzi, Serenella M. Pupa, Marilena V. Iorio (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13263211.txt.
Description
Angela Galardi and six co-authors review the two-way traffic between blood clotting and cancer in a 2026 article. Clotting normally repairs blood vessels, but tumors hijack the same machinery. In turn, clotting factors help tumors grow, spread, and hide.
Tumor cells switch on clotting proteins and signals that open new blood vessels and blunt immune attack. Neighboring support cells in the tumor are pushed to make clotting factors too. Platelets coat traveling tumor cells, shielding them from stress and immune killers, while fibrin mats give tumors a scaffold and recruit suppressive cells. Clot-driven signals also help push immune cells out of the tumor's core. The review gathers this loop into one picture. It argues that the clotting system is not a bystander in cancer but an active partner, and a possible target.
Catalog record
| CREATOR | Angela Galardi, Elisa Dell’Orto, Francesca Bianchi, Giulia Cosentino, Valentina Fogazzi, Serenella M. Pupa, Marilena V. Iorio |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |