Protective effects of human umbilical cord mesenchymal stem cells-derived small extracelluar vesicles on corneal epithelial cells under hyperosmotic stress: Inhibition of oxidative damage and inflammation
Chengyu Peng, Mingqi Zhang, Yuqing Bao, Zhuoshi Wang, Fenglei Zhang, Wei He · 2026
Read Protective effects of human umbilical cord mesenchymal stem cells-derived small extracelluar vesicles on corneal epithelial cells under hyperosmotic stress: Inhibition of oxidative damage and inflammation by Chengyu Peng, Mingqi Zhang, Yuqing Bao, Zhuoshi Wang, Fenglei Zhang, Wei He (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13262691.txt.
Description
Chengyu Peng and co-authors test tiny packages released by stem cells as a treatment for dry eye injury in a 2026 journal article. Dry eye can leave the cornea's surface cells under hyperosmotic stress, stress from overly salty tears, which kills cells and slows healing. The packages came from stem cells taken from human umbilical cords.
In lab tests, the vesicles helped human corneal surface cells grow and repair under that stress. They lowered oxidative damage, chemical harm from unstable oxygen molecules, and kept the cells' energy centers working. They also reduced two inflammation signals and quieted a pathway that drives inflammation. The authors propose the vesicles as a possible new treatment route.
Catalog record
| CREATOR | Chengyu Peng, Mingqi Zhang, Yuqing Bao, Zhuoshi Wang, Fenglei Zhang, Wei He |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28252 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |