First TES in Djibouti: A Critical Milestone Amid Rising Regional Threats

Sinknesh Wolde Behaksra, Samatar Kayad Guelleh, Solomon Sisay, Yisihak Abreham Weldehana, Daniel Mussa Weyesa, Tirhas Endale, Assia Adlao Hamad, Natnael Lemessa Hundera, Dawit Hailu Alemayehu, Elias B Tafa, William Louie, Andres Aranda-Diaz, Meklit Shiferaw, Matiwos Kidane Ayele, Fikregabrail Aberra · 2026

Read First TES in Djibouti: A Critical Milestone Amid Rising Regional Threats by Sinknesh Wolde Behaksra, Samatar Kayad Guelleh, Solomon Sisay, Yisihak Abreham Weldehana, Daniel Mussa Weyesa, Tirhas Endale, Assia Adlao Hamad, Natnael Lemessa Hundera, Dawit Hailu Alemayehu, Elias B Tafa, William Louie, Andres Aranda-Diaz, Meklit Shiferaw, Matiwos Kidane Ayele, Fikregabrail Aberra (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13262534.txt.

Description

Sinknesh Wolde Behaksra and a large team reported in 2026 Djibouti's first therapeutic efficacy study of its frontline malaria treatment. Artemether-lumefantrine has served since 2014 without any in-country check of how well it still works. Their twenty-eight-day study at one Djibouti City clinic enrolled eighty-eight patients with uncomplicated falciparum malaria.

Seventy patients finished follow-up, and the corrected cure rate reached close to ninety-nine percent, with a single late failure. The drug therefore still works in Djibouti. Warning signs gathered elsewhere in the results: the common rapid test built on one parasite protein caught barely a third of infections, because nearly all parasites had deleted that protein's genes. Resistance-linked gene patterns were widespread, and sexual-stage parasites lingered for weeks. The authors urge combined molecular surveillance and transmission-blocking steps such as single-dose primaquine.

Catalog record

CREATORSinknesh Wolde Behaksra, Samatar Kayad Guelleh, Solomon Sisay, Yisihak Abreham Weldehana, Daniel Mussa Weyesa, Tirhas Endale, Assia Adlao Hamad, Natnael Lemessa Hundera, Dawit Hailu Alemayehu, Elias B Tafa, William Louie, Andres Aranda-Diaz, Meklit Shiferaw, Matiwos Kidane Ayele, Fikregabrail Aberra
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE34 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13262534

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