Clinically relevant genomic and phenotypic differences in virulence, antimicrobial resistance, and biofilm-associated tolerance between Streptococcus suis lineages ST1 and ST123
Cristina Uruén, Clara M Marín, Luis Daniel González-Vázquez, Marcelo Gottschalk, Miguel Arenas, Jesús Arenas · 2026
Read Clinically relevant genomic and phenotypic differences in virulence, antimicrobial resistance, and biofilm-associated tolerance between Streptococcus suis lineages ST1 and ST123 by Cristina Uruén, Clara M Marín, Luis Daniel González-Vázquez, Marcelo Gottschalk, Miguel Arenas, Jesús Arenas (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13262394.txt.
Description
Streptococcus suis infects pigs and the people who handle them, and Spain watches two of its lineages with different habits. Cristina Uruén and co-authors compare ST1, a lineage found worldwide, with ST123, which surfaced in Spain within the last decade, in a 2026 study.
The two share about fourteen hundred genes, roughly three fifths of the genome, while each carries over a hundred private genes, some on genomic islands handling special sugars. ST123 varied more from strain to strain. In mice both lineages caused body-wide infection but lingered in different tissues. ST123 clung less well to immune cells and survived worse inside them, yet it could learn ampicillin resistance in the laboratory. Layered films of bacteria, biofilms, also set the two apart in drug tolerance. The comparison explains a newcomer's rise.
Catalog record
| CREATOR | Cristina Uruén, Clara M Marín, Luis Daniel González-Vázquez, Marcelo Gottschalk, Miguel Arenas, Jesús Arenas |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 73 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |