Olfactory Outcomes After Endoscopic Sinus Surgery for Chronic Rhinosinusitis With Nasal Polyposis

Elysia Grose, Jenny B Xiao, Patrick Macinnis, Yvonne Chan, John M Lee · 2026

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Description

Elysia Grose and colleagues present a 2026 prospective study of smell outcomes after endoscopic sinus surgery for chronic sinus inflammation with nasal polyps. Loss of smell is a hard-to-treat symptom in this condition. The team measured outcomes with both a symptom questionnaire and an odor identification test.

The single-center study enrolled 36 adults operated on between July 2022 and May 2024; 45% were female and the mean age was 48. Mean SNOT-22 symptom scores fell from 57 before surgery to 22, 15, and 25 at 1, 3, and 6 months. Odor identification improved from 5.2 of 16 odors to 7.9, 8.3, and 7.7 at the same visits. Improvements were statistically significant at every follow-up. The authors conclude surgery can meaningfully improve smell, while noting longer studies must test whether gains last.

Catalog record

CREATORElysia Grose, Jenny B Xiao, Patrick Macinnis, Yvonne Chan, John M Lee
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE23773
LICENSEhttps://creativecommons.org/licenses/by/4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/article/MED/PMC13261535

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