Hypoglycemic Encephalopathy Caused by Insulinoma With Reversible High Signals in the White Matter on Diffusion‐Weighted MRI: A Case Report
Taira Shiratori, Iichiro Osawa, Wataru Watanabe, Keita Nagawa, Koichiro Matsuura, Shinji Kakemoto, Morihiro Higashi, Eito Kozawa, Shashank Kaushik · 2026
Read Hypoglycemic Encephalopathy Caused by Insulinoma With Reversible High Signals in the White Matter on Diffusion‐Weighted MRI: A Case Report by Taira Shiratori, Iichiro Osawa, Wataru Watanabe, Keita Nagawa, Koichiro Matsuura, Shinji Kakemoto, Morihiro Higashi, Eito Kozawa, Shashank Kaushik (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13261534.txt.
Description
Taira Shiratori and co-authors report a 2026 case of hypoglycemic encephalopathy caused by an insulinoma. An insulinoma is a rare pancreatic tumor that secretes too much insulin, driving blood sugar dangerously low. The resulting brain dysfunction can mimic epilepsy and leave bright signals on special MRI scans.
Their patient was a 66-year-old man with recurrent involuntary movements, impaired consciousness, and psychiatric symptoms, without any diabetes treatment history. His blood glucose was critically low at 29 mg/dL. Diffusion-weighted imaging showed reversible bright signals in white matter, including the internal capsule, corona radiata, and corpus callosum. A fasting test and contrast CT confirmed the insulinoma. Intravenous glucose brought rapid improvement, and symptoms resolved fully within one day. Surgeons removed part of the pancreas. Follow-up imaging at two months showed complete resolution of the brain changes.
Catalog record
| CREATOR | Taira Shiratori, Iichiro Osawa, Wataru Watanabe, Keita Nagawa, Koichiro Matsuura, Shinji Kakemoto, Morihiro Higashi, Eito Kozawa, Shashank Kaushik |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 23988 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |