Beyond the primary site: Molecular insights and clinical implications of cancer metastatic overlap between lung and urological organ cancers (Review)
Yinhuan Wang, Jiefang Guan · 2026
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Description
Yinhuan Wang and Jiefang Guan review cancers that wander between the lungs and the urinary organs. Prostate, kidney, and bladder tumors trade metastatic ground with lung cancer often enough to confuse diagnosis and treatment. Their 2026 review gathers the molecular threads behind this two-way overlap.
The tumor types share escape toolkits, including a chemokine homing axis and a growth factor pathway that loosens cell identity. Each organ's immune neighborhood then shapes how arriving cells behave and respond to drugs. Blood-based biopsies and molecular profiling are sharpening the detective work. Even so, organ-specific soil keeps bending drug efficacy, demanding personalized plans.
Catalog record
| CREATOR | Yinhuan Wang, Jiefang Guan |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 59 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |