Residential green space mitigates genetic susceptibility to incident irritable bowel syndrome in a prospective cohort of 376 749 individuals
Zhifu Kou, Rui Li, Jingjie Wang, Zhongjun Shao, Jin Feng, Mengna Wei, Ting Fu, Lan Chen, Guzhengyue Zheng, Hualiang Lin, Kun Liu · 2026
Read Residential green space mitigates genetic susceptibility to incident irritable bowel syndrome in a prospective cohort of 376 749 individuals by Zhifu Kou, Rui Li, Jingjie Wang, Zhongjun Shao, Jin Feng, Mengna Wei, Ting Fu, Lan Chen, Guzhengyue Zheng, Hualiang Lin, Kun Liu (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/PMC13261328.txt.
Description
Zhifu Kou and colleagues present a 2026 prospective cohort study of residential green space, genes, and irritable bowel syndrome. IBS is a chronic bowel disorder with recurring pain and changed bowel habits. Whether nearby greenery interacts with genetic risk was unexplored.
The study included 376,749 UK Biobank participants, with greenness measured by a satellite vegetation index. Over 11.73 years of follow-up, 7,091 new IBS cases were documented. Within a 1000 m buffer, each interquartile-range rise in greenness meant a 5% lower IBS risk. Greater distance to water was also linked to lower risk. The green-space benefit appeared only in high-genetic-risk people, who saw an 8% risk reduction. No interaction appeared for blue space. Physical activity partly explained the green-space link. The authors commend urban greening as a prevention strategy.
Catalog record
| CREATOR | Zhifu Kou, Rui Li, Jingjie Wang, Zhongjun Shao, Jin Feng, Mengna Wei, Ting Fu, Lan Chen, Guzhengyue Zheng, Hualiang Lin, Kun Liu |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34095 |
| LICENSE | https://creativecommons.org/licenses/by/4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |