Expression of progranulin (GP88) protein appears as an independent prognostic factor for clinical progression in high-risk prostate cancer patients

Renata Dubrovska, Markus Eckstein, Rudolf Jung, Charis Kalogirou, Burkhard Kneitz, Martin Spahn, Marianna Kruithof-de Julio, Ginette Serrero, Binbin Yue, Carol Geppert, Robert Stöhr, Arndt Hartmann, Bernd Wullich, Verena Lieb, Helge Taubert, Sven Wach · 2026

Read Expression of progranulin (GP88) protein appears as an independent prognostic factor for clinical progression in high-risk prostate cancer patients by Renata Dubrovska, Markus Eckstein, Rudolf Jung, Charis Kalogirou, Burkhard Kneitz, Martin Spahn, Marianna Kruithof-de Julio, Ginette Serrero, Binbin Yue, Carol Geppert, Robert Stöhr, Arndt Hartmann, Bernd Wullich, Verena Lieb, Helge Taubert, Sven Wach (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13260916.txt.

Description

Renata Dubrovska and co-authors study a growth protein in high-risk prostate cancer in a 2026 paper. Prostate cancer is the second most common cancer in men. High-risk cases still lack good markers for who will progress.

The protein, progranulin or GP88, supports cell survival and growth. Past work linked it to outcomes in primary disease. Tissue arrays from high-risk patients were stained for the protein. Expression was then tied to clinical progression over time. The marker held up as an independent factor. Readers learn of a candidate test to sort high-risk patients by likely course.

Catalog record

CREATORRenata Dubrovska, Markus Eckstein, Rudolf Jung, Charis Kalogirou, Burkhard Kneitz, Martin Spahn, Marianna Kruithof-de Julio, Ginette Serrero, Binbin Yue, Carol Geppert, Robert Stöhr, Arndt Hartmann, Bernd Wullich, Verena Lieb, Helge Taubert, Sven Wach
YEAR2026
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC13260916

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