Treatment outcomes of daptomycin- and vancomycin-resistant Enterococcus faecium bloodstream infection
Wei-Ting Lin, Jia-Ling Yang, Chi-Ying Lin, Sung-Hsi Huang, Yu-Chung Chuang, Jann-Tay Wang, Yee-Chun Chen, Shan-Chwen Chang · 2026
Read Treatment outcomes of daptomycin- and vancomycin-resistant Enterococcus faecium bloodstream infection by Wei-Ting Lin, Jia-Ling Yang, Chi-Ying Lin, Sung-Hsi Huang, Yu-Chung Chuang, Jann-Tay Wang, Yee-Chun Chen, Shan-Chwen Chang (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13260658.txt.
Description
Wei-Ting Lin and co-authors compare in this 2026 study drug doses for a bloodstream infection that shrugs off two antibiotics. Among 130 patients with resistant Enterococcus faecium in the blood, most received high-dose daptomycin anyway, the rest linezolid. The team asked whether pushing the dose past a threshold saves lives.
Twenty-eight-day death ran about fifty-five percent on the lower dose band against thirty-four percent on the higher, a gap that survived adjustment. The benefit concentrated in isolates at one resistance level and vanished at higher ones. Linezolid's small group fared no better after adjustment. The authors frame the dose effect as a lead needing bigger trials.
Catalog record
| CREATOR | Wei-Ting Lin, Jia-Ling Yang, Chi-Ying Lin, Sung-Hsi Huang, Yu-Chung Chuang, Jann-Tay Wang, Yee-Chun Chen, Shan-Chwen Chang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |