Efficacy and safety of TiaoPi AnChang decoction to reduce CAPOX-Induced adverse reactions in Chinese patients with colorectal cancer: a randomized, double-blind, placebo-controlled trial
Jincheng Zhang, Yantong Guo, Zhan Hua, Meng Liu, Tao Fu, Wu Ning, Lei Zhou, Tao Tang, Xin Song, Chao Wang, Shaoxuan Chen, Dakui Zhang, Haibin Liu, Guochao Zhang, Jianzheng Jie, Zhiqiang Cheng · 2026
Read Efficacy and safety of TiaoPi AnChang decoction to reduce CAPOX-Induced adverse reactions in Chinese patients with colorectal cancer: a randomized, double-blind, placebo-controlled trial by Jincheng Zhang, Yantong Guo, Zhan Hua, Meng Liu, Tao Fu, Wu Ning, Lei Zhou, Tao Tang, Xin Song, Chao Wang, Shaoxuan Chen, Dakui Zhang, Haibin Liu, Guochao Zhang, Jianzheng Jie, Zhiqiang Cheng (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13260633.txt.
Description
Jincheng Zhang and a large team reported in 2026 interim results from a trial of a Chinese herbal decoction for easing chemotherapy side effects. Patients with colorectal cancer received the CAPOX drug regimen after surgery, and many suffer fatigue, nausea, and nerve damage. Their randomized, double-blind trial assigned 108 patients to the decoction or a matched placebo across four treatment cycles.
Overall adverse reactions occurred less often in the decoction group, with a clear gap for moderate-or-worse reactions. Fatigue, nausea, vomiting, appetite loss, and oxaliplatin-related nerve symptoms all improved. The formula did little for low blood counts, hand-foot syndrome, or pain. Quality of life scores improved, and no extra liver or kidney injury appeared. Survival endpoints had not yet been reached when this interim report was written.
Catalog record
| CREATOR | Jincheng Zhang, Yantong Guo, Zhan Hua, Meng Liu, Tao Fu, Wu Ning, Lei Zhou, Tao Tang, Xin Song, Chao Wang, Shaoxuan Chen, Dakui Zhang, Haibin Liu, Guochao Zhang, Jianzheng Jie, Zhiqiang Cheng |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 68 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |