Copper and cuproptosis-related genes as indictors for the diagnosis of injury time in traumatic brain injury: human cases and animal experiment
Rui Gu, Xiaojin Yu, Yaqing Tan, Guoliang Li, Longlong Suo, Runtao Ding, Hui Yao · 2026
Read Copper and cuproptosis-related genes as indictors for the diagnosis of injury time in traumatic brain injury: human cases and animal experiment by Rui Gu, Xiaojin Yu, Yaqing Tan, Guoliang Li, Longlong Suo, Runtao Ding, Hui Yao (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13259861.txt.
Description
Rui Gu and co-authors investigated in 2026 whether copper levels and copper-linked cell death can reveal when a traumatic brain injury happened. Forensic doctors often lack steady markers for dating such injuries. The team paired tests on human postmortem brain tissue with experiments in injured mice.
Copper built up in the bruised area of human brains over the 30 days after injury, rising in step with time. Mouse tissue showed signs of cuproptosis, a copper-driven form of cell death, in the same region. Certain genes, among them FDX1, DLD, and SLC31A1, tracked the early stage after injury. Other genes, LIAS and SLC31A1, fit the later stage better. The authors propose these measures as candidate tools for estimating injury timing.
Catalog record
| CREATOR | Rui Gu, Xiaojin Yu, Yaqing Tan, Guoliang Li, Longlong Suo, Runtao Ding, Hui Yao |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |