Obesity Triggers Dysregulation of Essential ABC Transporters in Rat Testis and Sperm
Péter Szatmári, Kata Kira Kemény, Adrienn Seres-Bokor, Eszter Ducza · 2026
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Description
Péter Szatmári and colleagues ask whether obesity quietly rewires the transport proteins that guard male fertility. ABC transporters pump substances in and out of cells in the testis and sperm. Feeding rats a fatty, sugary diet for ten weeks, their 2026 study watches two of them closely.
The diet made rats heavier, glucose-intolerant, and left them with smaller reproductive organs. In the testis, one transporter's gene and protein output rose while a second transporter's message fell. In sperm, both transporters' messages dropped. Testosterone and its control genes stayed unchanged, suggesting fertility risks can start before hormone trouble shows.
Catalog record
| CREATOR | Péter Szatmári, Kata Kira Kemény, Adrienn Seres-Bokor, Eszter Ducza |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |