Deciphering the Structure–Immunomodulatory Function Relationships of Homopolysaccharides
Gege Hu, Bingyu Yang, Han Song, Yuehan Zeng, Zhuoting Zhang, Yuwen Li, Jian Zhang, Fenghuan Wang · 2026
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Description
Gege Hu and co-authors map how single-sugar polysaccharide structure drives immune effects in a 2026 review. These long chains, built from one sugar type, act as bioactive nutrients with anti-infection and anti-inflammatory records. Extraction and structure methods are summarized before findings are sorted into a three-level framework.
Primary recognition covers weight, linkage style, branching, and shape, the features immune receptors actually read. Middle levels trace signaling through gut microbes and metabolite networks, including classic inflammatory pathways. Top levels refine outcomes by chemical modification and dose context. Gut and immune researchers gain a shared vocabulary joining carbohydrate chemistry to nutrition science. Fine structure measurement remains the field's bottleneck, and the authors propose modeling that joins structure data across many studies.
Catalog record
| CREATOR | Gege Hu, Bingyu Yang, Han Song, Yuehan Zeng, Zhuoting Zhang, Yuwen Li, Jian Zhang, Fenghuan Wang |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 64 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |