Nasal Epithelial Organoids as Translational Platforms in Inflammatory, Infectious, and Precision Medicine Applications: A Systematic Review
Veronica Scocca, Lorenzo Lauda, Riccardo Nocini, Giovanni Dell’Aversana Orabona · 2026
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Description
Veronica Scocca and three co-authors survey nose-lining organoids, tiny lab-grown balls of a patient's own nose cells, in this 2026 review. The nose lining is the first wall against germs and a hub of swelling signs. Balls of its cells can stand in for the real wall in a dish. The team hunted five data banks for all such work from 1990 to early 2026.
Seventeen studies met the bar. Their uses fell in three heaps: germ growth in the dish, swelling and wall reshaping, and drug tests for cystic fibrosis. Most grew the balls in gel or spread them flat at an air face. Germ runs showed each strain's own growth and defense tale. For the gene ill, ball swell tests tracked how well a drug freed the faulty pump. Mixed ways of work blocked one pooled count.
Catalog record
| CREATOR | Veronica Scocca, Lorenzo Lauda, Riccardo Nocini, Giovanni Dell’Aversana Orabona |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |