Diagnostic Potential of Apparent Diffusion Coefficient-Based Lymph Node Classification in Breast Cancer Patients Undergoing [18F]FDG-PET/MRI
Helena A. Peters, Marie Scheuer, Daniel Weiss, Matthias Boschheidgen, Vivien Lorena Ivan, Frederic Dietzel, Svjetlana Mohrmann, Eugen Ruckhäberle, Ken Herrmann, Harald H. Quick, Aleksandar Milosevic, Peter Minko, Julian Kirchner, Lale Umutlu, Gerald Antoch, Kai Jannusch · 2026
Read Diagnostic Potential of Apparent Diffusion Coefficient-Based Lymph Node Classification in Breast Cancer Patients Undergoing [18F]FDG-PET/MRI by Helena A. Peters, Marie Scheuer, Daniel Weiss, Matthias Boschheidgen, Vivien Lorena Ivan, Frederic Dietzel, Svjetlana Mohrmann, Eugen Ruckhäberle, Ken Herrmann, Harald H. Quick, Aleksandar Milosevic, Peter Minko, Julian Kirchner, Lale Umutlu, Gerald Antoch, Kai Jannusch (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13257417.txt.
Description
Helena A. Peters leads a 2026 imaging study that classifies chest lymph nodes in breast cancer staging. One hundred thirteen newly diagnosed patients underwent combined PET and MRI scans between 2017 and 2021. Nearly two hundred nodes were measured for size and for a diffusion value that reflects tissue density.
Nodes taking up the tracer strongly were far larger and showed much lower diffusion values. A single diffusion cutoff separated tracer-positive from tracer-negative nodes with near-perfect accuracy in the sample. Sensitivity and specificity both sat in the high nineties at that threshold. The tracer result itself served as the reference, which limits certainty against surgical proof. Radiologists still gain a strong candidate measure for node calls. Prospective checks against pathology would firm up the cutoff for routine staging decisions.
Catalog record
| CREATOR | Helena A. Peters, Marie Scheuer, Daniel Weiss, Matthias Boschheidgen, Vivien Lorena Ivan, Frederic Dietzel, Svjetlana Mohrmann, Eugen Ruckhäberle, Ken Herrmann, Harald H. Quick, Aleksandar Milosevic, Peter Minko, Julian Kirchner, Lale Umutlu, Gerald Antoch, Kai Jannusch |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |