Context-Dependent Alterations of E-Cadherin, β-Catenin, and Vimentin in Endometrial Ciliated Epithelial Change: An Exploratory Immunohistochemical Study
Teona Turashvili, George Tevdorashvili, George Burkadze · 2026
Read Context-Dependent Alterations of E-Cadherin, β-Catenin, and Vimentin in Endometrial Ciliated Epithelial Change: An Exploratory Immunohistochemical Study by Teona Turashvili, George Tevdorashvili, George Burkadze (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13257306.txt.
Description
Teona Turashvili and colleagues examine a puzzling lining change in womb tissue samples in a 2026 staining study. Ciliated change, where surface cells grow hair-like fringes, appears in benign and malignant lesions alike. Three hundred fifteen specimens from 2019 to 2024 were split evenly across seven diagnoses.
Digital analysis compared lesions with and without the ciliated change for three marker proteins. In benign categories, ciliated lesions showed less E-cadherin and more beta-catenin, often inside the nucleus. Cancers broke that pattern, showing opposite or weaker shifts. Vimentin fell consistently wherever ciliated change appeared. Two other markers gave mixed, less useful signals. Pathologists gain a caution: marker meaning depends on context, so a single stain cannot label these lesions as harmless or dangerous by itself.
Catalog record
| CREATOR | Teona Turashvili, George Tevdorashvili, George Burkadze |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |