Functional Diversity and Emerging Roles of Human NME/NDPK Group II Proteins
Bastien Proust, Helena Ćetković, Maja Jazvinšćak Jembrek, Maja Šutić, Lea Vrbančić, Maja Herak Bosnar · 2026
Read Functional Diversity and Emerging Roles of Human NME/NDPK Group II Proteins by Bastien Proust, Helena Ćetković, Maja Jazvinšćak Jembrek, Maja Šutić, Lea Vrbančić, Maja Herak Bosnar (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13256974.txt.
Description
Bastien Proust leads a 2026 review of the less-studied half of the human NME protein family. These enzymes mainly keep nucleotide building blocks in balance inside cells. Group I members are well mapped, while Group II members remain poorly understood.
Group II proteins carry one or more kinase domains yet differ widely in sequence. Most were long thought to be inactive as enzymes, with NME6 as the exception. Recent work hints at wider roles in gene control, DNA repair, and lipid handling. The review gathers that scattered evidence and sorts what is firm from what is still guesswork. For molecular biologists, the value lies in a clear map of open questions. Several family members now look worth targeted experiments rather than continued neglect.
Catalog record
| CREATOR | Bastien Proust, Helena Ćetković, Maja Jazvinšćak Jembrek, Maja Šutić, Lea Vrbančić, Maja Herak Bosnar |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |