Intestinal Absorption and Anti-Inflammatory Effects of a Low-Molecular-Weight α-Glucan from Flammulina filiformis
Yue Li, Mengmeng He, Ziyi Xu, Jianhui Liu, Haoru Zhao, Qiuhui Hu, Fei Pei, Wenjian Yang, Anxiang Su · 2026
Read Intestinal Absorption and Anti-Inflammatory Effects of a Low-Molecular-Weight α-Glucan from Flammulina filiformis by Yue Li, Mengmeng He, Ziyi Xu, Jianhui Liu, Haoru Zhao, Qiuhui Hu, Fei Pei, Wenjian Yang, Anxiang Su (2026) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-13256856.txt.
Description
Yue Li and co-authors describe in 2026 a small-chain polysaccharide from the edible mushroom Flammulina filiformis and show that, unlike its larger kin, it can cross the intestinal wall. Most mushroom polysaccharide research credits big molecules that act through gut microbes, leaving the absorbable small fraction largely unexamined.
Structural analysis showed the molecule is an α-glucan built from linked glucose units. Labeled copies crossed a layer of grown intestinal cells mainly through macropinocytosis, a gulping uptake route. In immune cells provoked with bacterial toxin, the glucan cut production of nitric oxide and several inflammatory messengers. The findings place small mushroom glucans as bioavailable candidates for anti-inflammatory foods.
Catalog record
| CREATOR | Yue Li, Mengmeng He, Ziyi Xu, Jianhui Liu, Haoru Zhao, Qiuhui Hu, Fei Pei, Wenjian Yang, Anxiang Su |
|---|---|
| YEAR | 2026 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 37 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |